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Human Genome
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    original Courtesy: U.S. Department of Energy Genomics:GTL Program, https://genomicscience.energy.gov http://cancergenome.nih.gov/ind nome-dna-seqencing.gif Courtesy: Human Genome Program, U.S. Department of Energy, To Know Ourselves, 1996 How to determine a DNA Sequence http://genome-map.org/images/ge Genome Programs, https://genomics.energy.gov https://www.llnl.gov/str/June03 /gifs/Stubbs1.gif Courtesy: Lawrence Livermore National Laboratory http://www.amnh.org/learn/musings/FA01/ia/HW_01.jpg Courtesy: National Human Genome Research Institute bases in DNA nucleotides are adenine, thymine, cytosine and guanine. A = adenine T = thymine C = cytosine G = Guanine http://www.ornl.gov/sci/techres ources/Human_Genome/publicat/primer2001/99-1395man.jpg Courtesy: U.S. Department of Energy What is a genome? DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule and the sugar molecule deoxyribose. The KU_hoz_pos_KO.eps THE HUMAN GENOME PROJECT The Human Genome Project Department of Energy National Institutes of Health original Courtesy: U.S. Department of Energy Genome Programs genomics.energy.gov Prior to the Human Genome Project The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. (Note that a gene would actually be a much longer stretch of DNA than what is shown here.) Courtesy: National Institute of General Medical Sciences Sources consulted for this presentation 1000 Genomes Project . (2010). Retrieved from http://www.genome.gov/27528684 American Museum of Natural History. (n.d.). Retrieved from http://www.amnh.org/learn/musings/FA01/ia/HW_01.jpg Biological and Environmental Research Information System. (2010). Human Genome Project Information. Retrieved from http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml A Brief Guide to Genomics. (2010). Retrieved from http://www.genome.gov/18016863 The Cancer Genome Atlas. (n.d.). Retrieved from http://cancergenome.nih.gov/about/history.asp Cracking the Code of Life. (2001). Retrieved from http://www.pbs.org/wgbh/nova/genome/ Genome Map. (n.d.). Retrieved from http://genome-map.org/images/genome-dna-seqencing.gif Human Genome Program, U.S. Department of Energy, Genomics and Its Impact on Science and Society: A 2008 Primer. (2008). Retrieved from http://www.ornl.gov/sci/techresources/Human_Genome/publicat/primer2001/ The Human Genome Project, A Decade Later. (2010). Retrieved from http://www.pbs.org/newshour/extra/features/science/july-dec10/genome_07-07.html Image Gallery. (n.d.). Retrieved from http://genomics.energy.gov/gallery/ International HapMap Project. (2010). Retrieved from http://www.genome.gov/10001688 National Institute of General Medical Science (2010). The New Genetics. Retrieved from http://publications.nigms.nih.gov/thenewgenetics/chapter1.html#c1 National Institutes of Health. (2007). A Guide to Your Genome. Retrieved from http://www.genome.gov/Pages/Education/AllAbouttheHumanGenomeProject/GuidetoYourGenome07.pdf National Institutes of Health Human Genome Project Fact Sheet. (n.d.). Retrieved from http://www.nih.gov/about/researchresultsforthepublic/HumanGenomeProject.pdf Office of the Inspector General (2004). The FBI DNA Laboratory: A Review of Protocol and Practice Vulnerabilities. Retrieved from http://www.justice.gov/oig/special/0405/ US Department of Energy Office of Science. (2009). DOE Genomic Science Program Overview. Retrieved from http://genomicscience.energy.gov/pubs/GenomicScienceProgramBrochure_11-12-09.pdf ntent/hgp2010.jpg Courtesy: U.S. Department of Energy Genome Programs, http://genomics.energy.gov International HapMap Project ex.asp The Cancer Genome Atlas Courtesy: the National Cancer Institute Cancer Genome Atlas Impacts on research and future applications http://www.genome.gov/images/co